The Scientific Committee acts as the supervisory body authority of the CoBi.
The tasks of the Scientific Committee are:
- Providing scientific evaluation of research projects
- Providing guidance on steps to be taken in case of individual incidental genetic findings
Prior to the approval, the research request of a Principal Investigator has to pass through a completeness check (Access Application Form) and a compliance check according the Access Policy of the CoBi.
The decision to approve a research request will be taken solely by the Scientific Committee within a time frame of eight weeks and a maximum time frame of 16 weeks in the event of change requests or queries.
The Scientific Committee consists of seven votes in total and four membership groups:
- Transplantation Centres (represented by 2 votes, elected by all Transplantation Centres involved in the CoBi)
- DKMS (represented by 2 fixed votes)
- Immunogeneticists (2 votes)
- Statistician (1 vote)
Projects will be evaluated exclusively with respect to the scientific merit and impact on the defined research framework of the Collaborative Biobank. Specifically, the following issues shall be evaluated:
- Is the current knowledge with respect to the research question summarized correctly?
- Is the hypothesis of the research purpose formulated precisely?
- Is the proposed methodology appropriate?
- Is the statistical plan conclusive?
- What might be the impact on future donor selection?
The Scientific Committee is quorate if at least 4 votes are cast.
For the coordination and administration of the Scientific Committee, DKMS Clinical Trials Unit undertakes all Committee Secretary Processes (e.g. compile background documents, count votes, draw-up approval notices).
Current members of the Scientific Committee:
|PD Dr. med. Gesine Bug||
Universitätsklinikum Frankfurt, Goethe-Universität, Medizinische Klinik 2
|Prof. Dr. med. Katharina Fleischhauer||Universitätsklinikum Essen, Institut für Zelltherapeutische Forschung|
|Dr. Vinzenz Lange||DKMS Life Science Lab GmbH|
|Prof. Dr. Hein Putter||Leids Universitair Medisch Centrum|
|Univ.-Prof. Dr. med. Johannes Schetelig||DKMS Clinical Trials Unit & Universitätsklinikum Carl Gustav Carus Dresden, Medizinische Klinik und Poliklinik I|
|Univ.-Prof. Dr. med. Matthias Stelljes||Universitätsklinikum Münster, Bereichsleiter Knochenmarktransplantationszentrum|
|Prof. Dr. Robert Zeiser||Universitätsklinikum Freiburg, Klinik für Innere Medizin I, Hämatologie, Onkologie und Stammzelltransplantation|